Objectives: Breast carcinoma is the second most common type of cancer globally, with an estimated 2.08 million new carcinoma cases identified in 2018 itself. Breast cancer prognosis is influenced by a number of variables, including the patient’s age, morphological variant, stromal inflammatory reaction, elastotic, fibrotic focus, lympho-vascular emboli, recurrence of tumor, etc. Recently, the morphological evaluation and extent of tumor-infiltrating lymphocytes (TIL) have also been studied in breast cancer. An attempt is being made to understand the role of TIL in determining the prognostication of carcinoma breast. Thus, the goal of the current academic study is to assess TIL in breast carcinoma. 

Materials and method: The study was performed at a medical institution’s pathology department, which included newly diagnosed cases on histopathology of infiltrating ductal carcinoma of the breast during January 2019 to December 2019. The gross and hematoxyline-eosin-stained paraffin sections were studied for histopathological examination. 

Results: The study included 50 cases of infiltrating ductal carcinoma of the breast with a female-to-male ratio of 24:1. Stromal TIL was negative (0-10%) in 12 cases, while was positive (11-100 %) in 38 cases. The results were analysed by the receiver operating characteristic (ROC) curve, which indicated the specificity of 70.7% and the sensitivity of 85.3% when the cutoff of stromal TIL <11% was used to predict the live status of patients.