Dr. Yun-Chen Chang
China Medical University, TaiwanTitle: Impact of web-based mindfulness-based stress reduction (wMBSR) on cortisol and melatonin breast cancer survivors during the COVID-19 - Mixed method results of a controlled intervention study
Abstract
Background and Aim: During the
COVID-19 pandemic, a web-based mindfulness-based stress reduction (wMBSR)
program delivery format, delivered over the Internet, may be a better choice
compared with face-to-face MBSR. The present study focused on evaluating the
effects of wMBSR intervention on cortisol and melatonin in female breast cancer
in Taiwan.
Materials and Methods:
Face-to-face and telephone interviews using a standardized interview guide.
Triangulation of qualitative and quantitative data allowed for a more thorough
understanding of the effects of wMBSR. Eighteen breast cancer survivors were
received 6-week wMBSR (n=18) program. Patients requested to collect saliva
samples 20 minutes (approximately 09:00) prior to the first (T0), third (T1),
and sixth sessions (T2). Quantitative analysis of paired t-test and two-way
ANOVA was used to analyze the data. Qualitative analysis of constant comparison
method.
Results: Regarding endocrine
hormone levels measurements, the average session means of the three melatonin
values of pre-intervention were in line with post-intervention (p=.416), having
results of 4.27, 5.88 and 5.01 pg/ml, respectively. Cortisol levels likewise
did not alter substantially from preto post-intervention (p=.067), having
results of 1161.82, 1071.41, and 975.72 pg/ml, respectively. Three salient
themes emerged from our qualitative analysis, namely (a) Negative body image
and sexual problem among patients with breast cancer, (b) Self-aware of the
stress of life, but will try to practice, (c)The support of a patient peer
group.
Conclusion: This study is a pilot
study to explore the endocrine effects of wMBSR on female breast cancer
patients. During the COVID-19 pandemic, for healthcare professionals to improve
endocrine changes using web-based clinical health education, additional samples
and face-to-face cohorts will need to be collected in the future.
Biography
Yun-Chen Chang graduated from
National Taiwan University, Taiwan. She is the assistant professor of the School
of Nursing and Graduate Institute of Nursing of China Medical University,
Taiwan and supervisor of the Nursing Department, at China Medical University
Hospital, Taichung, Taiwan. Her areas of expertise are breast cancer care, mindfulness-based,
complementary and alternative medicine and interventions. She has been serving
as an editorial board member of some reputed journals.