Background: Breast cancer is the leading cause of morbidity and mortality among women in many countries around the globe. Early detection of breast cancer plays a great role in cancer prevention and treatment by potentially decreasing mortality. However, evidence is sparse on breast cancer screening practice among women in southern Ethiopia. Therefore, the aim of this study was to assess breast cancer screening practice and associated factors among women 20–70 years of age in an urban setting in SNNPR, Ethiopia.

Methods: A community-based cross-sectional study was conducted from March to April 2020. Multistage sampling technique was applied to select the study participants. Data were collected by using a pretested interviewer-administered structured questionnaire. Bivariable and multivariable logistic regression was done to confirm association between dependent variable and covariates.

Results: From the total study participants, 83 (13.6%; 95%CI: 10.8, 16.4%), have regularly engaged in at least one breast cancer screening method. Women with a favorable attitude towards breast cancer and its screening (AOR=3.0; 95%CI: 1.63–5.56), educational status of college and above (AOR=3.8; 95%CI: 1.25– 11.48), family history of breast cancer (AOR=3.7; 95%CI: 1.73–7.96), awareness about breast cancer screening methods (AOR=3.0; 95%CI: 1.46–6.22), knowing someone screened for breast cancer (AOR=2.2; 95%CI: 1.10–4.38), and recommendation by health professionals for BCS (AOR=5.0; 95% CI: 2.35–10.68) were variables significantly associated with BCS practice.

Conclusion: Breast cancer screening practice is low. Women with college and above education level, favorable attitude towards breast cancer and its screening, awareness about breast cancer screening methods, family history of breast cancer, having a recommendation from health professionals and knowing someone who screened for breast cancer were associated with BCS practice. Therefore, this finding implies the need to intervene upon those factors.

I had completed his MPH in Epidemiology at the age of 31 years from Hawassa, Ethiopia. I’m focal person of research publication and grant management office at Hawassa college of health science, Ethiopia. I have over 15 publications that have been cited by different articles. I had been served as an editorial board member of some reputable journals.