Sattama Samanta
Department of Radiation Oncology, Medical College Kolkata, IndiaPresentation Title:
PHOTON VERSUS ELECTRON BOOST- WHICH IS THE OPTIMAL OPTION AFTER BREAST CONSERVATION SURGERY? : A DOSIMETRIC STUDY
Abstract
Background: Breast cancer patients undergoing breast conservation surgery(BCS) receive whole breast irradiation(WBI) followed by a tumour bed boost, as a part of standard adjuvant therapy. This study aims to compare the dosimetric outcomes of using photon beams versus electron beams for such boost.
Methods: 36 patients who had undergone BCS and received WBI with 40 Gy in 15 fractions followed by a 12 Gy in 6 fractions tumour bed boost with a photon based plan, were included in this study. They were replanned using electron beams for the tumour bed boost. The DVH (Dose-Volume Histogram) parameters-V95%, V90%, V85%, D50%, CI(Conformity Index) for the boost-cavity-PTV(Planning Target Volume); the OAR(Organs at Risk) doses, particularly- mean dose and V2Gy for Ipsilateral Lung, V3Gy and V10Gy for Ipsilateral Breast, mean doses for each of Contralateral Lung, Contralateral Breast, Heart and a 5mm-thick-skin-segment covering ipsilateral breast surface, were noted for both the plans and compared.
Results: In our study, there was a statistically significant difference between photon and electron boost plans in terms of PTV dosimetry parameters, in favour of photon boost plan (p value<0.05). Better Conformity Index(CI) was seen with the photon boost plan as well(p=0.016). The mean dose(p=0.0027) and V2Gy(p=0.0002) for Ipsilateral Lung, skin mean dose(p=0.0013) were also significantly lower in photon boost plans compared to the electron boost plans. Contrarily, the V3Gy(p=0.0004) and V10Gy(p= 0.018) for Ipsilateral Breast were significantly lower in electron plans. However, the mean doses for heart, contralateral breast, and contralateral lung did not vary significantly.
Conclusions: Most of the parameters assessed in our study, favour a photon boost. Notably, lower mean dose for skin, implying better cosmetic outcomes, was observed with photon boost. However, certain factors like tumour depth, beam energy selected, have considerable influence on the. outcomes and further studies are warranted in future.
Biography
Dr. Sattama Samanta completed her MBBS in the year 2019 from Calcutta National Medical College, Kolkata with
Honours at the age of 24 and is currently a dedicated Junior Resident Doctor pursuing a MD degree in Radiation
Oncology in the Department of Radiation Oncology of Medical College, Kolkata. She has actively participated in
multiple workshops, quizes, as well as international, national and state conferences where she has presented
insightful posters and presentations on various oncological studies. Recently, her research work has been accepted
for publication in a reputed international journal. In addition to clinical duties, Sattama is engaged in continuous
learning and research, aiming to stay at the forefront of advancements in radiation oncology.
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