Resection of periampullary carcinoma can be performed in fifty to sixty percent of people, although pancreatic cancer resection is a viable treatment option in ten to twenty percent of cases. Periampullary carcinoma has a more favorable prognosis after surgical resection. This study aimed to determine the most important predictors of fistula formation after pancreaticoduodenectomy for periampullary carcinoma. Methods: This was observational study that included 20 individuals to undergo pancreaticoduodenectomy for periampullary carcinoma in Helwan University Hospitals. Results: There was highly significant variation among the two groups concerning drain amylase plus drain lipase.

Ali Hussein has completed his PHD at the age of 40 years from Helwan University, Egypt. He is a member of liver transplant team in NHTMRI .He did about 50 cases of Whippl,s  procedures. He participate in about 100 cases of living donor liver transplant. He is a member of general surgery council in general surgery fellowship.