Parvovirus B19 (PB19) is a small, single-stranded DNA virus that is commonly spread by respiratory secretions or from hand to mouth contact, but can also occasionally be transmitted from the mother to the fetus during pregnancy. Approximately 50–75% of women of reproductive age have developed immunity to PB191. Although pregnancy has been shown not to affect the natural history of the infection, seronegative pregnant women, once exposed to the virus, can transmit the infection to their fetus in approximately 17–33% of cases. Parvovirus B19 infection may be asymptomatic or may present with prodromal symptoms only. In some cases, the prodrome is followed by a subsequent phase with more specific symptoms, while in other cases, as in immunosuppressed or high-risk individuals, the infection may progress to a chronic form associated with long-term complications and sequelae.Non-immune pregnant women are at risk for fetal infection by parvovirus B19, with greater complications if transmission occurs in the first or second trimester. Infected fetuses may not show any abnormalities in most cases, but in more severe cases, there may be severe fetal anemia, hydrops, and even pregnancy loss. Maternal diagnosis of intrauterine parvovirus B19 infection includes IgG and IgM antibody testing. For fetal diagnosis, PCR is performed through amniocentesis.

Majda BOURADDANE is a PhD student researcher from the CLAUDE BERNARD University of Lyon-1 2012-2016 in allergology immunology. His research has focused on: allergy to olive pollen in Marrakesh, Morocco, prevalence of E.coli in the Mediterranean marine environment and biochemical and molecular characteristics of pathogenic strains, research by PCR and RT-PCR of Enterovirus in shellfish samples. And currently his research is focused on the seroprevalence of Parvovirus B19 in pregnant women in Marrakesh, Morocco for his national doctorate. She is currently in charge of initial and continuing training at a research and innovation centre at the Marrakesh Faculty of Medicine and of practical immunology and microbiology work.