5th International conference on Cancer Prevention and Research

Cancer biology and genetics form the foundation for understanding the molecular and cellular mechanisms that drive cancer initiation, progression, and resistance to therapy. This session explores breakthroughs in cancer genetics, tumor microenvironment research, and molecular oncology that pave the way for precision medicine and innovative cancer prevention strategies. By integrating preventive oncology, cancer epidemiology, and healthcare research, it emphasizes how genetic alterations, epigenetics, and signaling pathways contribute to cancer risk and progression. Attendees will gain insights into how these discoveries enhance early detection, guide targeted therapies, and support global cancer initiatives to reduce the worldwide cancer burden. 

Molecular Pathways Driving Cancer Initiation and Progression 

Understanding the molecular pathways involved in cancer development is crucial for identifying therapeutic targets. This sub-topic highlights key signaling pathways, oncogene activation, and tumor suppressor gene loss that influence cancer risk, progression, and treatment response. 

Role of Oncogenes and Tumor Suppressor Genes in Cancer Biology 

Oncogenes and tumor suppressor genes regulate cell growth and division. This sub-topic examines how their mutations drive uncontrolled proliferation, explores diagnostic biomarkers, and discusses targeted therapeutic interventions that enhance cancer prevention strategies and precision-based oncology care. 

Epigenetic Modifications and Their Role in Tumor Development 

Epigenetic changes such as DNA methylation, histone modification, and chromatin remodeling influence cancer biology without altering the DNA sequence. This sub-topic highlights their role in tumor initiation, progression, and how these insights guide innovative cancer therapy research. 

Genomic Instability and Chromosomal Aberrations in Cancer 

Genomic instability is a hallmark of cancer, leading to mutations and chromosomal abnormalities. This sub-topic discusses the mechanisms behind genomic instability, its contribution to cancer heterogeneity, and implications for early detection and personalized prevention strategies. 

Tumor Microenvironment and Its Influence on Cancer Progression 

The tumor microenvironment—including immune cells, blood vessels, and signaling molecules—plays a critical role in tumor growth and metastasis. This sub-topic explores innovative research on targeting the microenvironment to improve cancer therapy outcomes and preventive oncology measures. 

Genetics of Cancer Metastasis and Therapeutic Resistance 

Metastasis and treatment resistance remain major challenges in oncology. This sub-topic focuses on the genetic drivers of metastasis, molecular mechanisms of resistance to therapies, and how these insights inform global cancer initiatives for advanced treatment development.